Fibromyalgia caused by abnormal skin? Skin abnormalities source of fibromyalgia A study from the Albany Medical College published in Pain Medicine provided an interesting set of findings. The investigators biopsied the palms of patients with fibromyalgia and found an excessive number of nerve fibers involved in temperature regulation. This may contribute to pain in the hands, altered blood flow to the muscles and abnormalities in circadian blood flow leading to fatigue, pain, and sleep disturbances. Commen nteresting and provocative.